New compound preparation of iodized oil
In order to achieve accurate real-time imaging of tumor during embolization, to guide the embolization treatment and precise resection of liver cancer, HONGPU Fu company independently developed the Superstable Homogeneous Iodized Formula Technology (SHIFT).The new compound preparation of iodized oil prepared by this technology can solve the problems of poor dispersion of drug molecule - iodized oil solvent, rapid separation of mixed solvent in vivo and poor treatment effect. Compared with the traditional mixing method, shift iodized oil compound preparation:
(1) mixes the iodized oil with drug molecules physically, without introducing other cosolvents or emulsions, which is safe in performance;
(2) the prepared iodized oil drug preparation is not easy to agglomerate, and can be stably placed for 30 days at room temperature, with superior stability;
(3) does not affect the focus deposition of iodized oil and does not hinder the performance of drug molecules, It can even enhance the signal intensity of fluorescence developing molecules. Corresponding scientific research has published SCI papers in Journal of controlled release, the top medical journal. We are cooperating with hospitals to carry out clinical research and accelerate clinical transformation.
The VX2 model of rabbit was established and the interventional embolization of SHIFT (lipiodol -ICG) was performed by DSA
Surgical navigation resection effect